Wednesday, February 20, 2008

Novocell - stem cells control diabetes in mice

I see this news is being reported in several places. It's interesting because there's been so much talk about using stem cells to treat diabetes. Now Novocell says that they were able to use human stem cells to control diabetes in mice.



Now before you say anything, I do know that things which work for mice don't always work for humans(PDF). But unfortunately most of this research does use NOD (Non obese diabetic) mice, so we're stuck with that for the present.

This approach is not yet perfect because some of the mice developed tumors. I'm guessing that we won't see anything come out of these labs for several years.

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11 Comments:

At February 20, 2008 4:14 PM , Blogger Anne said...

another good day for diabetic mice!! This is very exciting; I hadn't seen the news yet.

 
At February 20, 2008 5:26 PM , Blogger Courtney said...

the question i have is: how do they know the mice are diabetic to begin with? are they breeding diabetic mice or what?

 
At February 20, 2008 5:48 PM , Blogger marias23 said...

very cool. i've seen this pop up all over the media. do you have the link to the primary article? i would so love to read it.

 
At February 20, 2008 7:41 PM , Blogger Anne said...

here's the abstract
http://www.nature.com/nbt/journal/vaop/ncurrent/abs/nbt1393.html

 
At February 20, 2008 7:59 PM , Blogger Bernard said...

Courtney

That link I provided to the Wikipedia article on NOD mice says that these mice "exhibit a susceptibility to spontaneous development of automimmune insulin dependent diabetes mellitus". There's something in these mice that causes them to get diabetes or other auto-immune diseases.

These are the same mice that Dr. Faustman and others have used to test cures for type 1 diabetes.

 
At February 21, 2008 11:00 AM , Blogger mollyjade said...

Didn't they artificially create the diabetes in these mice by feeding them a toxin to destroy their beta cells? We still have to come up with a solution to the autoimmunte part of type 1.

 
At February 22, 2008 12:36 PM , Blogger Windy said...

Bernard,
Can you email me at WindyCobourne@gmail.com when you get a chance? I have a couple questions for you about Dr. Faustman's research but don't want to cutter up your comment page. Thanks!

 
At February 24, 2008 3:40 PM , Blogger k2 said...

Score 1 for the Diabetic Mice!

Meeses don't fail us know!

Kelly K

 
At February 24, 2008 3:44 PM , Blogger k2 said...

CORRECTION
Meeses don't fail us NOW!

 
At March 10, 2008 11:34 AM , Blogger gina said...

we are having a scientist from the DRI come talk about this. on march 19

 
At March 10, 2008 11:55 AM , Blogger Bernard said...

Gina

Is that at DiabetesTalkFest?

That should be really interesting. Unfortunately I'll be at a conference so I won't attend.

 

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