Inject once before meals Diabetes365 day 15
If I told you I had diabetes and that I needed to inject something before meals, you might say "Oh yeah, insulin right?".Well I'm wearing an insulin pump, so I don't actually inject insulin before meals, I use the pump to deliver it. But for about a year I've been injecting Symlin before most meals that I eat.
When I'm in the office, I just roll up my trouser leg and inject there shortly before eating.
Symlin is an artificial version of amylin, another hormone produced by the pancreas, in the beta cells. If you don't have type 1 diabetes, this hormone slows down the emptying of food from your stomach and makes you feel fuller (increasing satiety). It also seems to slow down the release of glucagon from your liver.
The net result is that my blood sugar doesn't go up as quickly as it normally would after eating. So it helps me maintain better control of my blood glucose levels.
Because it slows down food getting into your system, Symlin can cause severe lows that are difficult to treat. In my case I can also go low just from taking Symlin without mealtime insulin. This may be due to the glucagon suppression and a basal insulin level that's effectively too high when Symlin is being used.
I also had terrible nausea for the first month that I used Symlin. So bad that it made me not want to eat. But that's passed now. Even if I don't take Symlin for a few days, the nausea doesn't return.
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Labels: diabetes, diabetes365, symlin
posted by Bernard @ 8:26 AM
6 Comments:
Symlin, by itself, cannot cause lows -- unfortunately, only insulin can cause lows with or without amylin. Symlin may make lows more difficult to treat, but just remember the guilty party here: insulin.
Bernard - what happens if you take symlin before a ride, I imagine that would destroy any chance at an endurace activity.
A friend of mine took Symlin for a while. But it made her so sick she had to lay down in our boss's office one day. The doctor told her the nausea would pass after a while. But, unfortunately, she wasn't able to handle it.
I'm glad it doesn't make you feel sick anymore. That was probably a rough time for you to get through that stage.
Bernard, I'm going to see an endocrinologist in a few weeks (for the first time in 25 years...I've been managing my diabetes just with a family Dr.) One of the things I'm considering is Symlin. Given your personal experience - would you do it again? Are the benefits worth the negatives?
Thx,
Scott
Scott Powell
If I went off Symlin and had to restart it with the nausea, I'd still do it. The difference in my control is very profound.
I need to write a separate post about Symlin. One trick is to just start on a low dose and let your body get used to that (maybe a week or more) and then increase it by 3 units and wait another week until the nausea has gone. Now I take 15 units before most meals and it's just amazing the difference - I may get a post meal high of 150 after 2 hours instead of 280 after 1 hour.
I hope this helps.
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