Calcineurin and diabetes
I just read this press release about a protein called calcineurin and its effect on insulin-producing cells.According to the article, when this protein is suppressed insulin producing cells do not multiply as much and insulin production is reduced, leading to diabetes in the mice that were used for experiments. The Stanford research team then found that by activating NFAT (nuclear factor of activated T cells) in the beta cells, the cells then behaved normally multiplying and producing the usual amounts of insulin.
I did some searching around and found this research article from 2001 that appears (as best I can understand it) to say much the same thing. It seems this research may best help those with Type 2 diabetes.
It's interesting that this shows yet another way in which insulin production can be knocked out and recovered from. What amazing things our bodies are.
posted by Bernard @ 7:08 AM
1 Comments:
I also read the article on calineurin. Unfortunately, it will do nothing for those of us who have T1DM. It will however benefit those who have Type 2 Diabetes and those who are "targeted" to get Diabetes. Alas, after all these years, T1DM is still a barren land compared to what is available for Type 2 in regards treatment and prevention.
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